Eye Physics (EP) plaques are much refined descendants of the plaque designs that were found to be the most useful at the University of Southern California (USC) from 1980 to 2010.
The first USC plaques were originally prototyped for Ir-192 seeds in the early to mid 1980s by LAC/USC physicist David Neblett (who in 1988 created the ROCS treatment planning program for the PC) and jeweler Jerry Schuber of nearby Commerce CA. The primitive seed positioning slots enabled the Ir-192 seeds to be mounted in reproducible loading patterns. These early Ir-192 plaques were retired in the late 1980s in favor of more refined second generation prototypes intended for I-125 seeds. Jerry sadly passed away of ALS disease in 2014.
In the late 1980s USC physicist Melvin Astrahan began development of the Plaque Simulator (PS) treatment planning software, worked with Jerry Schuber to revise the earlier USC Ir-192 plaque designs for I-125 seeds, prototyped many new plaque designs with much deeper seed positioning slots intended to also individually collimate the low energy radiation emitted by I-125 seeds, and eventually developed for PS the technology to prototype plaques using stereolithographic 3D printing. All EP plaques are compatible with seeds containing low energy radionuclides other than I-125 (e.g. Pd-103) so long as they conform to the now standardized cylindrical dimensions 0.8 x 4.5 mm.