Version 6 of Plaque Simulator (PS6) is designed for recent (2009 models or later) Apple Macintosh computers with Intel Xeon, Core i5, i7 or i9 multicore processors that can install OSX version 10.11 or greater. As of March 2019, Eye Physics recommends running PS6 on the fastest computer you can afford (e.g. ≥3.46 GHz) with at least 4 processor cores, at least 16 GB of RAM and OSX 10.14.3 (Mojave). Support for MacOS 10.13 (High Sierra) requires PS6 version 6.6.1 or later and MacOS 10.14 (Mojave) requires PS6 version 6.6.7 or later.
Intel Xeon and Core i7 and i9 processors are hyper-threaded which means that for each processor core that is physically present, the operating system addresses two virtual or logical cores, and shares the workload between them when possible. The Intel Core i5 processor found in many off-the-shelf iMacs and Mac laptops has less cache and the 4 core variant is not hyper-threaded. These computers may, however, be ordered with an upgrade to Core i7 or i9 processor at the time of purchase at a slightly higher price. PS6 will run on the Core i5 processor but dosimetry performance will be slower than on an i7 or i9 6 or 8 core processor.
Plaque Simulator version 6.2 and later leverages multicore processors when performing all 2D, 3D and histogram dosimetry calculations. For instance, when running on the hyper-threaded 4 core Xeon processor, PS6 distributes its dosimetry calculations uniformly and concurrently amongst 8 logical cores, resulting in a 5X acceleration compared to running on a single logical core. The acceleration factor is about 7X on a 6 core processor and at ≥12X on a 12 core processor.
Eye Physics recommends running PS6 on the fastest hyper-threaded multicore processor (e.g. 12 core Xeon, 4 core i7, 6 or 8 core i9) that your institution can afford in order to achieve the best overall user experience possible. For any given processor speed, increasing the number of cores will proportionally increase the speed of multidimensional dosimetry calculations, resulting in more rapid isodose line, isodose surface and dose histogram comparisons of alternative plan options. OSX leverages the GPUs on the video card to accelerate some graphics and many features of the operating system, so choosing the most powerful video capability offered at the time of purchase (or as an after-market upgrade for 2009-2012 desktop Mac Pros) is also desireable.
The software development system as of March 2019 is a 2009 Mac Pro desktop (aluminum tower case) which has been upgraded from its stock configuration to firmware MacPro5,1 and a pair of 3.46 GHz 6-Core Intel Xeon processors (total 12 physical cores, 24 logical cores), an 802.11ac+Bluetooth_4 mini PCIe card, a generic Sapphire Radeon Nitro+ RX 580 8GB GDDR5 Dual HDMI / DVI-D / Dual DP w/ Backplate Special Edition (UEFI) PCI-E Graphic Card 11265-21-20G. This card works fine for dual 30 inch monitors and MacOS 10.14, but it was not flashed for MacOS booting so we dont see the initial MacOS boot screen (booting from an SSD is so fast that its not an issue) and an inexpensive dual 6-pin to single 8-pin power adapter was required), a 4 port USB3 PCI card, a 2TB Samsung 860 SSD boot drive mounted on a PCI SATA3 adapter card and 4 WD Black series 6TB hard disks, a DVD-RW optical drive, and 64 GB RAM running under MacOSX 10.14.3 (Mojave). Peripherals include a pair of Dell 30" ultrasharp UP3017 display monitors, Epson 4870 and 4990 Photo flatbed scanners with VueScan software and either an HP Color LaserJet Pro M254dw printer. All of the 2009 Mac Pro upgrade components are available on ebay and/or from various other internet vendors.
To get the most from Plaque Simulator you will want to do image based planning. Eye Physics uses the following well known 3rd party software solutions to prepare CT, MR, ultrasound and fundus images for export to Plaque Simulator.